University of Chicago

What you'll study

The PhD in Biology combines foundational coursework, laboratory rotations and an extended independent research project leading to a dissertation. In the first year students typically undertake multiple laboratory rotations to identify a long‑term thesis laboratory, while completing core coursework in areas such as molecular biology, genetics, cell biology, developmental biology, physiology, ecology and evolution. Training emphasises both experimental and quantitative methods, with opportunities to take classes in computational biology, bioinformatics, biophysics and statistics.

• Core coursework and seminars: graduate-level courses in molecular and cellular biology, genetics, and organismal biology, plus journal clubs and departmental seminar series.
• Laboratory rotations: short-term placements in different research groups to gain practical skills and decide on a thesis laboratory.
• Qualifying requirements: written and/or oral qualifying examinations to assess readiness for independent research, followed by formation of a dissertation committee and proposal defence.
• Research and dissertation: multi‑year original research under the mentorship of a faculty advisor, culminating in a defended written dissertation and publications in peer‑reviewed journals.
• Electives and interdisciplinary options: opportunities to take courses or collaborate with units such as the Committee on Evolutionary Biology, the Computation Institute, the Institute for Molecular Engineering and affiliated research centres.

Entry requirements

Applicants should hold a strong undergraduate degree in biology or a closely related discipline (for example biochemistry, bioengineering, physics, mathematics or computer science with significant biological coursework). Successful candidates typically demonstrate substantial laboratory research experience, evidence of scientific potential, and strong academic performance.

• Academic background: a relevant bachelor’s degree; a master’s degree can be advantageous but is not required.
• Research experience: sustained hands‑on research in an academic or industrial laboratory, with responsibilities that demonstrate initiative and technical competence.
• Application materials: academic transcripts, a CV, a personal statement outlining research interests and fit with the department, and three or more letters of recommendation from researchers who can speak to research ability.
• English language: proof of proficiency for applicants whose first language is not English, according to the university’s established requirements.
• Selection process: short‑listed applicants are typically invited for interviews (remote or on campus) with faculty and current students as part of the final admissions decision.

Career prospects

Graduates of the PhD programme pursue diverse careers across academia, industry and the public sector. Traditional paths include postdoctoral research positions leading to faculty roles in universities and research institutes. Many alumni also move into research scientist positions in biotechnology and pharmaceutical companies, roles in computational biology and bioinformatics, scientific leadership in translational research, and technology development.

• Academic research and teaching (postdoctoral fellowships, tenure‑track faculty)
• Industry research and development (biotech, pharma, contract research organisations)
• Computational and quantitative biology roles in data‑driven companies
• Science policy, management, and translational research administration
• Entrepreneurship and biotech start‑ups

Why study at University of Chicago

The University of Chicago offers a rigorous, research‑intensive environment with strong emphasis on quantitative and conceptual training. The Department of Biology houses faculty working across molecular, cellular, developmental, neurobiological, evolutionary and ecological domains, enabling students to pursue interdisciplinary projects and benefit from broad expertise.

Students gain access to extensive core facilities, computational resources and collaborative centres that bridge biology with chemistry, physics, engineering and data science. The department’s seminar series, regular symposia and a collegial graduate community provide rich opportunities for networking, professional development and cross‑disciplinary mentorship.